|
週次 |
日期 |
單元主題 |
|
第0週 |
02/03 |
First meeting-王俊能老師 |
|
第1週 |
2/24 |
Introduction of phylogeography and its applications |
|
第2週 |
3/02 |
NCBI GenBank Data mining of population haplotypes: BLAST & Entrez surfing
|
|
第3週 |
3/09 |
Sequence histogram readings and finding PCR condition & cloning errors
|
|
第4週 |
3/16 |
Multiple sequence alignment (CLUSTALW) and haplotype assignment |
|
第5週 |
3/23 |
Manual and advanced primer design from web (Primers 3, codehops)
|
|
第6週 |
3/30 |
Markers for phylogeographic and population researches (nuclear & chloroplast, AFLP, SSR markers) |
|
第7週 |
4/06 |
Neutrality test & coalescence theory (DnaSP practice for Tajima’s D test)
|
|
第8週 |
4/13 |
Parameters for population genetic analysis (GenAlEx): genetic variation measures, heterozygosity, test for H-W equilibrium |
|
第9週 |
4/20 |
Detect population differentiation, genetic structure (FST, AMOVA in Arlequin) |
|
第10週 |
4/27 |
Genetic haplotype networks and Phylogeographic analysis (software: TCS genealogy and NCPA) |
|
第11週 |
5/04 |
Habitat heterogeneity, geographic barrier and genetic variance correlation (DIVA, mantel test, IBD) |
|
第12週 |
5/11 |
Assigning individuals to populations and metapopulations using structure program |
|
第13週 |
5/18 |
Demographic models and past population dynamics (ABC modeling, Baysien Skylight plot, mismatch analysis), bottleneck (m-ratio test, mode shift test, heterozygosity excess essay) |
|
第14週 |
5/25 |
Amount of genet flow and directions between populations (Migrate)
|
|
第15週 |
6/01 |
Detection of loci under selection: BayesFst, Bayescan, F-dist2, Hierarchial island model) |
|
第16週 |
6/08 |
Molecular clock calculations & Molecular Divergence Dating (BEAST, McMcCoal, Multidistribute) |
|
第17週 |
6/15 |
Final examination
|